Another Hair Loss Gene Discovered

An earlier study done by researchers at Bonn and Dusseldorf Universities found the first hair loss gene inherited through the maternal X-chromosome. This discovery helped explain the similarity in hair loss between men and their maternal grandfathers. Now a study conducted by the same research teams at Bonn and Dusseldorf Universities report a second hair loss gene has been discovered. This new gene may explain the similarity of hair growth between a man and his father.

The study, published in Nature Genetics, conducted a genome-wide association in 300 participants with male-pattern baldness (androgenetic alopecia) and 300 control participants. Researchers investigated over 500,000 variable sites in the genomes of the participants. Two regions corresponded with baldness in the participants. The first region of the genome was already known. The second region was new.

The researchers found that the newly discovered gene was located on chromosome 20, that can be inherited both maternally and fraternally.  This new genome can be associated with premature hair loss.  Since the new gene can be inherited from both mother and father, it helps explain hair growth similarity between father and son.

"We are now trying to discover the role played by this genomic region in hair-growth", Dr. Felix Brockschmidt of Bonn University states in a news release. "Only then will we know whether we on the right track for new forms of therapy for male hair-loss".

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