
Adverse drug events (ADEs) are a common complication that often requires hospitalization. Although children are increasingly being treated with prescription drugs, not much data was available about ADEs. Now research reports that kids' bad drug reactions are common, with over half a million children treated annually.
The study, published in Pediatrics, investigated the national incidence of pediatric ADEs. Researchers at Children's Hospital in Boston, analyzed data from the National Center for Health Statistics from 1995 to 2005. They tracked children's visits to clinics and emergency rooms seeking medical treatment for ADE.
The researchers found that 43 percent of visits to clinics and emergency rooms were made by children under 5, followed by 23 percent of visits by teens. Furthermore, over half a million hospitalized children have ADEs yearly. The drugs most often implicated in ADEs were antimicrobial drugs for children 4 years and younger, followed by birth control pills and central nervous stimulants for teens.
"ADEs result in a substantial number of health care visits, particularly in outpatient clinics," conclude the study authors. "The incidence of ADEs and medications implicated vary by age, indicating that age-specific approaches for monitoring and preventing ADEs may be most effective."
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