Inflammation is associated with aging and many chronic diseases including atherosclerosis (cholesterol-filled plaque in the arteries). Inflammatory markers including C-reactive protein and cytokines (interleukin-6) are known to be lower in older adults. Low levels of zinc are also associated with atherosclerosis and other chronic diseases. Now research reports that zinc supplementation may reduce inflammation and atherosclerosis risk.
The double-blind study, published in the American Journal of Clinical Nutrition, evaluated the effects of zinc treatment on atherosclerosis-related inflammatory markers. Researchers at the School of Medicine Wayne State University in Detroit, administered either 45 mg zinc or a placebo daily to 40 healthy subjects aged 56 to 83, for six months. Levels of inflammatory markers were obtained from the participants before and after treatment.
The researchers found that the zinc group had higher zinc concentrations, while the placebo group had unchanged zinc levels. Furthermore, the zinc group had increased antioxidant levels and reduced Inflammatory markers including C-reactive protein and interleukin-6.
“These findings suggest that zinc may have a protective effect in atherosclerosis because of its antiinflammatory and antioxidant functions,” the study authors conclude.
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